Study on adjusting indexes of lipidemia of prescription TT2 of the hypertension patients with lipidemia disorder

51 hypertension patients with lipidemia disorder were treated at Hospital of Military Traditional Medicine from April to September 2004. All patients were divided into 2 groups: The control group consisted of 19 patients who received Caropil 25mg tablet/ twice a day during 28 continuous days; the study group consisted of 32 patients who received a traditional recipe of TT2/per day divided into 2 times every 12 hours during 28 days. Among hypertension patients with primary lipidemia disorder and signs of phlegm wetness or and phlegm heat types, using a traditional recipe of T22/per day during continuous 28 days had effects of regulating the index of lipidemia: CT decrease of 14.9%; TG decrease of 27.5%; LDL-C decrease of 16.2%; the effects of increasing HDL-C were not significantly (increase of 6.5%).

Study on the impacts of the TT2 prescription in treating hypertension in the patients with blood lipid metabolism disorder

A study was carried out on 51 patients with hypertension and blood lipid metabolism disorder at the Clinic Department and Heart-Renal-Joint Department in the Military Traditional Hospital and at the General Enterology Department in the Son Tay Hospital from Feb 2004 to Sept 2004. The patients were divided into two groups: study group included 2 patients using a TT2 traditional repice/day for 28 days; control group included 9 patients using Caporil 25mg x 2 tablets/day for 28 days. 50 white mousses of Swiss species were provided by The National Institute of Hygiene and Epidemiology. TT2 experiment showed no acute toxicity with experimental dose 50g/1kg of mouse weight. Boiling and drinking a TT2 traditional repice/day did not cause any side effects. TT2 helps to decrease blood pressure significantly in patients with hypertension and blood lipid metabolism disorder. After 4 weeks, the blood pressure level in patients using TT2 is as equivalent as in patients using Caporil 25mg x 2 tablets/day. TT2 improves symptoms of the both of disease type: dizzy, headache, neck pain, dyspepsia, insomnia, lose appetite, red face, red eyes and constipation.

Study on the effects of the TT1 prescription in treating light and medium hypertension without blood lipid metabolic disorder

A controlled prospective study included 50 normal Swiss white mice and 62 patients with mild and moderate hypertension without blood lipid metabolic disorder were divided into two groups randomly. The control group: 31 patients treated by Caporil 25mg, two tablets twice daily, (at 12 hours intervals). The study group: 31 take a TT1 prescription daily within 28 days continuously. The result showed that: No acute toxicity from TT1 prescription on trial dose of white mice: 50g/kg. No side effects occur when the patient uses a TT1 prescription daily. No blood lipid metabolic disorder on mild and moderate hypertension patients. TT1 had clearly good efficacy on hypotension. This efficacy after two weeks treatment is less effective than Caporil 25mg, twice daily but equivalent with Caporil 25mg, twice daily after 4 weeks. Some symptoms such as dazzle, dizziness, headache, red face, red eyes, tightness on chest had improved by TT1 and it was much better than Caporil.

Study on clinical effects of a Chinese medicine formulation for hypertension patients with low and moderate risk

A control retrospective study included 67 hypertension patients from 18 to 70 years old in Clinical Hospital No 1, Guangzhou Pharmaceutical -Medicine University from 10/200 to 04/2002. Captopril 25 mg/day were given to all patients. The control group included 32 patients. Extract 150ml divided twice daily from malt for 28 days continuously. The study group included 35 patients use "thien ma cau dang am" formulation orally (oral Rhizoma Gastrodiae Ramulus and Uncariae cum Uncis formulation), one packet boiled two times, taken 150ml twice for 28 days continuously. Result: In the hypertension patients with low and moderate risk: Combination of western medicine (Captopril) and traditional medicine (thien ma cau dang am) reduced blood pressure; relieved or prevented symptoms compare to captopril taken alone. Control group: 68.75% compare with study group: 91.43%; p = 0.001. Thien ma cau dang am treat hypertension has better effect than untreatment. It also reduced side effects of Captopril.